Skip to Content
Where did I come from?
Phylogenetic Relationships among Humans
Allan Wilson and his colleagues Mark Stoneking and Rebecca Cann estimated the phylogenetic relationships among the humans whom they sampled. Here you will need to examine their results closely to decide which of the competing hypotheses is supported. There are two parts: examining the phylogenetic relationships among modern human populations and estimating the age of the common ancestor of all modern humans, and of all non-Africans.
One of the major outcomes of this study is a phylogenetic tree of relationships. You can download this tree, and examine it closely to decide which hypothesis it supports.
Take a few minutes now to download and install FigTree, software for viewing and manipulating phylogenetic trees. Return to this window when you are ready to proceed. [Get FigTree]
Examine and Explore the Tree
Begin your exploration of the tree by downloading it. Cann87tree (1 KB) choose Save the Link As ... and save the file on your desktop computer. (Please extract zip file before use)
Now, start the FigTree software. Once it is started, from the File menu choose Open and select the tree file which you just downloaded.
The individual samples are coded with the geographic region of origin (Af = Africa, As = Asia, Au = Australia, Eu = Europe, NG = New Guinea).
The tree looks pretty complicated! [Have a peek.] How are you going to interpret this and compare it with the predicted trees?
There are some things that you can do to make the tree more manageable:
These actions should be bringing your tree into a more readable form, perhaps something like [this].
Interpret the Tree
Now you need to assess the tree, to decide whether it supports one or the other of the two hypotheses of human ancestry. Recall the differences in the trees predicted by the Multi-regional and Recent African Origin Hypotheses.
Here are some features of the tree which you need to consider:
Which hypothesis, Multi-regional or Recent African Origin, do you think is supported by this tree?
Age of Most Recent Common Ancestor
An important factor to be considered in deciding between the two hypotheses is the age of the most recent common ancestor of humans. The Multi-regional Hypothesis predicts an ancient ancestor, occurring about a million years ago, while the Recent African Origin Hypothesis predicts a much more recent common ancestor.
The age of the common ancestor of humans can be estimated using the molecular clock. Certain types of genetic changes accumulate at an approximately constant rate. We can estimate that rate by comparing organisms which have been separated for a known period of time. When we observe genetic differences between two other organisms, we can estimate the date of their common ancestor as
Date of common ancestor = Observed genetic difference / Rate of Genetic change
Wilson had earlier estimated that the rate at which RFLP genetic differences accumulated in human mtDNA was 2 - 4% per million years.
Look at your tree and try to find the common ancestors of the clades listed in the table below. Use Wilson's estimate of the rate of genetic change to infer the age of modern humans. What date do these results indicate for the origin of non-Africans?
|Clade of all humans||0.57%|
|Clade containing all non-Africans||0.45%|
|Oldest Clade containing no Africans||0.43%|
Why would we estimate these dates using both the high and low rates of genetic change?
Which hypothesis, Multi-regional or Recent African Origin, do you think is supported by these ages or dates?